In the past two decades, functional coating of small particles such as granules, pellets and mini-tablets has become an integral part of pharmaceutical development and production. However, the coating process introduced challenges concerning IPC and weight gain. Researchers typically work with theoretically calculated weight gain as well as “trial and error” experiments, supported by PSD measurements.
The traditional solution to this challenge derived from the tablet coating process, where tablets are usually counted in batches of 100 tablets, with repeated weighing during the process. The calculated average weight of one tablet shows when the target weight gain is reached.
But when particles had to be counted, the same procedure was impossible to follow due to the need to count thousands of particles.
The innovative solution to this problem came from DATA’s Pellet Counter, which allows users to count large amounts of particles.